In Graves’ disease, the immune system creates an abnormal antibody called thyroid-stimulating immunoglobulin. This antibody mimics the function of normal thyroid-stimulating hormone. The immune system produces antibodies that stimulate the thyroid gland to release excess amounts of thyroid produced hormones into the blood hyperthyroidism). Symptoms of Graves’ disease can include bulging eyes as well as weight loss, nervousness, irritability, irregular heart rate, and weakness.
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