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Male, 38 y/o

Patient internal ID: 368807765

ICD-10 code

C71.1 Malignant Neoplasm of the Frontal Lobe

Diagnosis (incl metastases/stage) and year

June 2019
High-grade Malignant Astrocytoma of the Frontal Lobe G2, IDH1 mutated. March 2020 – Tumour Recurrence: Brain Anaplastic Astrocytoma G3, IDH1 and ATRX mutated, Ki67 – 20%. Recraniotomy, Tumour Removal (08-04-2020).

Previous treatment

Surgery (craniotomy), chemotherapy (Temozolomide).

Prognosis and survival expectation

The prognosis remains poor, with a median survival of 33 months from diagnosis.

Treatment provided

Autologous DCV (10 doses) and CIK (4 doses) over a period of 14 months.
Additionally, the patient received nasal drops of exosomes with Paclitaxel.

Patient survival/condition and year

The patient is alive (now 52 months since diagnosis) with stable disease.
It can be concluded that the addition of Immunotherapy, alongside Surgery and Chemotherapy, has extended the patient’s survival by about 1 and a half years so far, compared with median survival.

Date of Review

15/10/2023