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Female, 37 y/o

Patient internal ID: 426175

ICD-10 code

C50.3 Malignant Neoplasm of Lower-Inner Quadrant of Breast

Diagnosis (incl metastases/stage) and year

April 2018
C50.3 Malignant Neoplasm of Lower Inner Quadrant of Breast. Right Breast Carcinoma cT4N2M1 G3, ER (-), PR (-), HER2 (0), Stage IV (2018-04). Status after Chemotherapy. Left Breast Carcinoma cT3N1. Metastases to the Skin, Lungs, Liver and Parasternal region of the Right Breast. Carcinoma Metastases in the Brain. Condition after Chemotherapy, Radiotherapy, Genetic Treatment, Craniotomy (2020-12-23). Hereditary Breast and Ovarian Cancer Syndrome (Pathogenic Heterozygous Variant of BRCA1 Gene).

Previous treatment

Radiation Therapy, Chemotherapy (Temozolomide), Target Therapy (Olaparib), Chemotherapy (Capecitabine), Chemotherapy (Eribulin).

Prognosis and survival expectation

The prognosis remains poor, with a median survival of ±13,3 months from diagnosis.

Treatment provided

Autologous DCV (4 doses) and CIK (4 doses) over a period of 4 months.

Patient survival/condition and year

The patient has survived 43 months from diagnosis. It can be concluded that the addition of Immunotherapy, together with Chemotherapies and Radiation Therapy, has extended the patient’s survival by about 2 and a half years compared with median survival.

Date of Review

15/10/2023