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Female, 62 y/o

Patient internal ID: 500119790

ICD-10 code

C50.8 Malignant Neoplasm of Overlapping Sites of Breast

Diagnosis (incl metastases/stage) and year

Carcinoma of Right Breast pT1miN0snM0, ER (+) 5%, PR (-), HER2 (3+), KI67 10%. DCIS (2012). In January 2013 recurrence of Right Breast Carcinoma rpT1aNxM0 G2 ER (-), PR (-), HER2(3+), DCIS/DIN3. Disease progression in May 2020: Metastases in Lung, Pleura, Pericardium, Mediastinum l/m. Lung Carcinomatous Lymphangitis, Fluid in Pericardium, Right Lung Carcinomatous Lymphangitis, in the Pleural Cavity.

Previous treatment

Surgery (Quadrantectomy), Surgery (Mastectomy), Radiation Therapy, Chemotherapy (Docetaxel) + Biological Therapy (Trastuzumab + Pertuzumab).

Prognosis and survival expectation

The prognosis remains poor, with a median survival of 13,3 months.

Treatment provided

Autologous DCV (4 doses) and CIK (4 doses) over a period of 5 months.

Patient survival/condition and year

Patient is alive, with stable disease and has survived 54 months after detection of Metastasis (progression). It can be concluded that the addition of Immunotherapy, alongside Surgery, Chemotherapies and Radiation Therapy, has benefited the patient with disease control and has
greatly extended her lifespan.

Date of Review

15/10/2023